This paper empirically analyses the effect a change of the saddle position in the sagittal plane (setback) by ±10mm has on the position of the knee joint as well as the pressure parameters central pressure point (COP), maximal pressure and loaded surface on the saddle.
Permalink: https://www.mendeley.com/catalogue/evaluating-central-pressure-point-determine-optimal-saddle-setback/.
Kraus L, Schade D, Natrup J
Journal of Science and Cycling (2015) 4(2)
English (UK) 
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